There are other names for the hematocrit, such as packed cell volume (PCV), volume of packed red cells (VPRC), or erythrocyte volume fraction (EVF). Both are potentially life-threatening disorders. An abnormally low hematocrit may suggest anemia, a decrease in the total amount of red blood cells, while an abnormally high hematocrit is called polycythemia. Hematocrit levels that are too high or too low can indicate a blood disorder, dehydration, or other medical conditions. It is a part of a person's complete blood count results, along with hemoglobin concentration, white blood cell count and platelet count.īecause the purpose of red blood cells is to transfer oxygen from the lungs to body tissues, a blood sample's hematocrit-the red blood cell volume percentage-can become a point of reference of its capability of delivering oxygen. The measurement depends on the number and size of red blood cells. A ratio of 3.5 +/- 0.2 may be helpful in cases of moderate anemia when typing only shows Hb A and E, to consider investigation for alpha-thalassemia, or in cases of alpha-thalassemia with acute blood loss, if the Hct is less than 35%, in the decision to transfuse.The hematocrit ( / h ɪ ˈ m æ t ə k r ɪ t/) ( Ht or HCT), also known by several other names, is the volume percentage (vol%) of red blood cells (RBCs) in blood, measured as part of a blood test. The underlying mechanisms for the higher Hct/Hb ratio among those with alpha-thalassemia are theorized to be less density and/or more hydration of a-thalassemia RBCs, more entrapment of plasma in the spun RBC, the high percent of nucleated RBC and WBC interference. The Hct/Hb ratios for each genotype of the alpha-thalassemia were not different from each other.

The mean Hct/Hb ratio in subjects with alpha-thalassemia was higher than the mean in normal subjects and in those with CKD. The Hct and Hb levels were derived by automated analyzer. We studied Hct/Hb ratios among patients with alpha-thalassemias (Hb H, H-CS, AEBart, AEBart-CS, EFBart and EFBart-CS diseases) diagnosed by high performance liquid chromatography, and compared them with normal subjects and with patients having anemia due to chronic kidney disease (CKD).

The ratio of hematocrit (Hct) to hemoglobin (Hb) in the people with normal red blood cell (RBC) morphology is generally three to one.

Test viscosity of hemoglobin in rbc